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published in(发表于) 2016/9/24 16:17:30 Edit(编辑)
A major breakthrough! Cancer cells were killed by Chinese doctors in this way

A major breakthrough! Cancer cells were killed by Chinese doctors in this way(重大突破!癌细胞被中国医生用这种方法弄死了)

English

中文

A major breakthrough! Cancer cells were killed by Chinese doctors in this way | cancer cells _ news

Cancer cells, with baking soda by Chinese doctors, "hungry" is dead



Hu during flood season



Chao ming


He and his research team found the "starving" new treatments for cancer, and published in the International Journal of biological and medical authority on elife, been affirmed by the world's leading oncologists.


"Cancer cells also need to ' eat ' things to survive, depriving it of food, cancer cells will die. "Said Xun Hu, Institute of Oncology of Zhejiang University Professor, is to follow this simple principle, and his research team discovered the" starving "new treatments for cancer, and published in the International Journal of biological and medical authority on elife, been affirmed by the world's leading oncologists.


After years of basic research, Xun Hu found that glucose is necessary of cancer cells "eat" anything and so the deprivation of glucose, cancer cells will die. But when glucose is in short supply, tumors did not starve also continued to grow.


Professor Xun Hu revealed the secret: the tumor in substantial numbers of lactate, lactic acid lactic acid dissociation into anion and hydrogen ions, becoming cancer cells in two "helpers", according to its own "food" on how much of "consumption".


The two "helpers" synergies, making cancer cells in glucose level is low, is very frugal use of glucose; in the absence of glucose enter "hibernate" State when glucose supply immediately to restore growth.


Therefore, if you want to effectively "starve" the cancer cells, not only deprivation of glucose, needed at the same time destroy the synergy of lactate anion and hydrogen ions. On the premise of glucose starvation or lack of, as long as the removal of any one of these two factors, cancer cells will die quickly.


Researchers with a base such as sodium bicarbonate (baking soda) to remove the tumors of the hydrogen ions, it may destroy the synergistic effect of lactate and hydrogen ions, which kills quickly and efficiently in glucose starvation or lack of tumor cells.


Basic research quickly into cancer therapy, more patients benefit from is the key.


Starting in 2012, has 30 years of clinical experience in the second affiliated hospital of Zhejiang University School of medicine Interventional doctor Chao ming Xun team hit it off, and Hu, into primary hepatocellular carcinoma in the study of new therapies, and the method name "targeting tumor lactate anion and hydrogen ions of arterial infusion chemoembolization," or "TILA-TACE".


Clinically, Chao ming explanation: "General artery intubation chemotherapy embolization (cTACE) cutting off the tumor's ' food ', then we will use sodium bicarbonate to remove tumors of the hydrogen ion, equivalent to not only to cancer ' eating ' and let it go to the gym quickly consume quickly ' starvation '. ”


Are welcome, they conducted clinical studies show: cTACE treated 37 patients, 18 cases of effective treatment of 40 patients with TILA-TACE, 40 cases effectively.


In the clinical study of TILA-TACE in the treatment of liver cancer is difficult to treat liver cancer.


International comprehensive report, cTACE treatment objective response rate an average of 35%. 35% to 100%, such a huge contrast in time to accept this not only their international counterparts, very seriously, even the two professors have been suspected in carrying out this research.


"The current preliminary statistics, the median survival time of patients, more than 3.5 years; subsequent big sample randomized controlled studies are needed, if proven to be effective for the treatment of liver cancer, is truly a leap forward. "The two experts said.


Source: Xinhua


Reporter: Huang Xiao



Responsible editor: Kun Qu SN117





Article keywords:
Cancer cells

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重大突破!癌细胞被中国医生用这种方法弄死了|癌细胞_新闻资讯

癌细胞,竟被中国医生用小苏打“饿”死了



△胡汛



△晁明


  他和研究团队一起发现了“饿死”癌细胞的新疗法,并发表在国际生物和医学领域权威杂志elife上,得到了国际著名肿瘤学者的肯定。


  “癌细胞也需要‘吃’东西才能生存,剥夺它的食物,癌细胞就会死亡。”浙江大学肿瘤研究所教授胡汛说,就是循着这个看似简单的原理,他和研究团队一起发现了“饿死”癌细胞的新疗法,并发表在国际生物和医学领域权威杂志elife上,得到了国际著名肿瘤学者的肯定。


  经过多年基础研究,胡汛发现葡萄糖是癌细胞必需“吃”的东西,照理看剥夺葡萄糖癌细胞就会死亡。但实际上葡萄糖供应不足时,肿瘤没有饿死还不断生长。


  胡汛教授道出了其中奥秘:肿瘤中有大量的乳酸,乳酸解离成乳酸阴离子和氢离子,成为癌细胞的两位“帮手”,让其自身能够根据“食物”的多少决定“消耗”多少。


  两位“帮手”协同作用,使得癌细胞在葡萄糖含量很少时,非常节约地利用葡萄糖;在没有葡萄糖的情况下进入“休眠”状态;当有葡萄糖供应时即刻恢复生长状态。


  因此,若想有效“饿死”癌细胞,不仅要剥夺葡萄糖,还需同时破坏乳酸阴离子和氢离子的协同作用。在葡萄糖饥饿或缺乏的前提下,只要去除这两个因子中的任何一个,癌细胞就会快速死亡。


  研究人员用碱如碳酸氢钠(小苏打)来去除肿瘤内的氢离子,就可破坏乳酸根和氢离子的协同作用,从而快速有效地杀死处于葡萄糖饥饿或缺乏的肿瘤细胞。


  将基础科研成果快速转化成肿瘤临床治疗,让更多患者受益是关键。


  2012年起,拥有30年临床经验的浙江大学医学院附属第二医院放射介入科医生晁明和胡汛团队一拍即合,投入到对原发性肝细胞肝癌新型疗法研究中,并将这种方法命名为“靶向肿瘤内乳酸阴离子和氢离子的动脉插管化疗栓塞术”,简称“TILA-TACE”。


  临床上,晁明给出解释:“常规动脉插管化疗栓塞术(cTACE)切断了肿瘤的‘食物通道’,然后我们再用碳酸氢钠去除肿瘤内的氢离子,相当于不仅不给肿瘤‘吃饭’,还让它去健身房快速消耗,迅速‘饿死’。”


  令人欣喜地是,他们进行的临床研究结果显示:用cTACE治疗了37例病人,18例有效;用TILA-TACE治疗了40例病人,40例有效。


  而且在这个临床研究中用TILA-TACE治疗的肝癌都是难治型肝癌。


  而国际上综合报道,cTACE治疗的平均客观有效率位35%。35%到100%,这样巨大的对比,不仅让国际同行在接受这篇文章时,非常慎重,就连两位教授也一直是带着怀疑在进行这项研究。


  “目前初步统计,病人的中位生存期,已超过三年半;后续还需要大样本的随机对照研究,如果证实有效,对肝癌治疗来说,确实是一个飞跃。”两位专家表示。


  来源:新华网


  记者:黄筱



责任编辑:瞿崑 SN117





文章关键词:
癌细胞

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